
Report on Carcinogens: Indium Compounds The National Toxicology Program recently released a request for public comment on nominations to the Report on Carcinogens (RoC). The RoC is a congressionally mandated, science-based, public health report that identifies substances that may pose an increased cancer risk. Each substance profile provides a review of the current human and animal cancer studies, the potential sources of exposure, and current Federal regulations limiting exposure. Indium compounds have been nominated to the RoC. The information requested includes: Data on current production and use patterns for indium products; Human exposure to indium; Information about ongoing or planned indium carcinogenicity studies; and Scientific issues important for assessing carcinogenicity. The deadline for submission of public comments on the nominated substances is February 28, 2012. Gradient routinely assists companies with evaluating exposure and carcinogenicity data and preparing regulatory comments. Please contact our team should you need assistance. Rare Earth Elements: Upcoming Events Gradient scientists are actively involved in the evaluation of sustainable development processes for rare earth element resources. We are participating in the following conferences: Ari Lewis, David Mayfield, and Kim Reid will present "Rare Earth Elements & Green Energy Technology: Preliminary Hazard Analysis" on Monday, January 30 at the Energy, Utility and the Environment Conference in Phoenix, Arizona. Neal Grasso will speak on Environmental Issues and Rare Earth Elements at the REE World's Technology Metals Summit 2012, February 1-2, 2012, in Toronto, Canada. Dave Mayfield and Neal Grasso will present "Environmental Issues Associated with Expanding Rare Earth Resources" during the Geology: Rare Earths: Markets and Policy session at the Annual Conference of the Society for Mining, Metallurgy & Exploration (SME), February 19-22 in Seattle, Washington.	For more information on Critical Metals, or Gradient's services, please contact: David B. Mayfield, M.S., DABT Senior Toxicologist dmayfield@gradientcorp.com Neal C. Grasso, M.S., P.G. Senior Geologist ngrasso@gradientcorp.com Ari S. Lewis, M.S. Environmental Health Principal Scientist alewis@gradientcorp.com Kim Reynolds Reid Senior Environmental Chemist kreid@gradientcorp.com Lorenz R. Rhomberg, Ph.D., FATS Principal lrhomberg@gradientcorp.com Gradient is an environmental and risk science consulting firm renowned for our specialties in Toxicology, Epidemiology, Risk Assessment, Product Safety, Contaminant Fate and Transport, and Environmental Chemistry. We employ sound science to assist national and global clients in resolving their complex problems relating to chemicals in the environment, in the workplace, and in consumer products.
(617) 395-5000 • www.gradientcorp.com • info@gradientcorp.com

Report on Carcinogens: Indium Compounds

The National Toxicology Program recently released a request for public comment on nominations to the Report on Carcinogens (RoC). The RoC is a congressionally mandated, science-based, public health report that identifies substances that may pose an increased cancer risk. Each substance profile provides a review of the current human and animal cancer studies, the potential sources of exposure, and current Federal regulations limiting exposure. Indium compounds have been nominated to the RoC. The information requested includes:

Data on current production and use patterns for indium products;
Human exposure to indium;
Information about ongoing or planned indium carcinogenicity studies; and
Scientific issues important for assessing carcinogenicity.

The deadline for submission of public comments on the nominated substances is February 28, 2012. Gradient routinely assists companies with evaluating exposure and carcinogenicity data and preparing regulatory comments. Please contact our team should you need assistance.

Rare Earth Elements: Upcoming Events

Gradient scientists are actively involved in the evaluation of sustainable development processes for rare earth element resources. We are participating in the following conferences:

Ari Lewis, David Mayfield, and Kim Reid will present "Rare Earth Elements & Green Energy Technology: Preliminary Hazard Analysis" on Monday, January 30 at the Energy, Utility and the Environment Conference in Phoenix, Arizona.

Neal Grasso will speak on Environmental Issues and Rare Earth Elements at the REE World's Technology Metals Summit 2012, February 1-2, 2012, in Toronto, Canada.

Dave Mayfield and Neal Grasso will present "Environmental Issues Associated with Expanding Rare Earth Resources" during the Geology: Rare Earths: Markets and Policy session at the Annual Conference of the Society for Mining, Metallurgy & Exploration (SME), February 19-22 in Seattle, Washington.

For more information on Critical Metals, or Gradient's services, please contact:

David B. Mayfield, M.S., DABT
Senior Toxicologist
dmayfield@gradientcorp.com

Neal C. Grasso, M.S., P.G.
Senior Geologist
ngrasso@gradientcorp.com

Ari S. Lewis, M.S.
Environmental Health Principal Scientist
alewis@gradientcorp.com

Kim Reynolds Reid
Senior Environmental Chemist
kreid@gradientcorp.com

Lorenz R. Rhomberg, Ph.D., FATS
Principal
lrhomberg@gradientcorp.com

Gradient is an environmental and risk science consulting firm renowned for our specialties in Toxicology, Epidemiology, Risk Assessment, Product Safety, Contaminant Fate and Transport, and Environmental Chemistry. We employ sound science to assist national and global clients in resolving their complex problems relating to chemicals in the environment, in the workplace, and in consumer products.